Description

2'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its precise molecular architecture serves as a key building block. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated phenylpropiophenone backbone.
• Chemical Research & Development: Serves as a versatile scaffold for organic synthesis and medicinal chemistry projects in academic and industrial labs.
• Material Science: Potential application in the synthesis of specialty polymers and liquid crystals due to its rigid molecular structure.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone
CAS No.	898789-85-0
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-(o-tolyl)propan-1-one; 3-(2-Methylphenyl)-1-(2-chloro-4-fluorophenyl)propan-1-one; 2'-Chloro-4'-fluoro-3-(2-methylphenyl)propiophenone; o-Tolyl 2-chloro-4-fluorophenyl ketone derivative; Propiophenone, 2'-chloro-4'-fluoro-3-(2-methylphenyl)-; CAS 898789-85-0
EINECS	Contact for details

Quality Control

Our 2'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.