Description

2,2-Dimethyl-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl-substituted propiophenone structure, which serves as a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Advanced Polymer Modifier: Incorporated into specialty polymer chains to impart specific characteristics such as altered solubility, thermal stability, or chemical resistance.
• Organic Synthesis & Method Development: A valuable substrate in academic and industrial laboratories for studying fluorination chemistry and developing new catalytic methodologies.

Basic Information

Product Name	2,2-Dimethyl-3',4',5'-Trifluoropropiophenone
CAS No.	898789-80-5
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	3',4',5'-Trifluoro-2,2-dimethylpropiophenone; 1-(3,4,5-Trifluorophenyl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(3,4,5-trifluorophenyl)propan-1-one; α,α-Dimethyl-3,4,5-trifluorophenyl ethyl ketone; 3,4,5-Trifluoro-α,α-dimethylpropiophenone; Propiophenone, 3',4',5'-trifluoro-2,2-dimethyl-; TFDPP (abbreviation)
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3',4',5'-Trifluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.