Description

3',5'-Difluoro-2,2-Dimethylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a critical precursor for the development of complex pharmaceutical intermediates and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Advanced Material Research: Employed in the development of novel polymers, ligands for catalysis, and other specialty materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom chemical synthesis services catering to the needs of biotechnology and fine chemical companies.

Basic Information

Product Name	3',5'-Difluoro-2,2-Dimethylpropiophenone
CAS No.	898789-77-0
Molecular Formula	C11H12F2O
Molecular Weight	198.21 g/mol
Synonyms	1-(3,5-Difluorophenyl)-2,2-dimethylpropan-1-one; 3,5-Difluoro-2,2-dimethylpropiophenone; 2,2-Dimethyl-1-(3,5-difluorophenyl)propan-1-one; α,α-Dimethyl-3,5-difluorophenylacetone; 3,5-Difluoro-α,α-dimethylphenylacetone; Propiophenone, 3',5'-difluoro-2,2-dimethyl-; 898789-77-0
EINECS	Contact for details

Quality Control

Every batch of 3',5'-Difluoro-2,2-Dimethylpropiophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including purity (HPLC/GC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.