Description

3',4'-Difluoro-2,2-Dimethylpropiophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms into complex molecules to modulate their biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used as a building block for developing new-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the production of advanced electronic materials for displays and lighting.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing novel fluorination methodologies in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3',4'-Difluoro-2,2-Dimethylpropiophenone
CAS No.	898789-74-7
Molecular Formula	C11H12F2O
Molecular Weight	198.21 g/mol
Synonyms	1-(3,4-Difluorophenyl)-2,2-dimethylpropan-1-one; 3,4-Difluoro-2,2-dimethylpropiophenone; 2,2-Dimethyl-1-(3,4-difluorophenyl)propan-1-one; α,α-Dimethyl-3,4-difluorophenylacetone; 3,4-DFDMP; Propiophenone, 3',4'-difluoro-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-2,2-Dimethylpropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.