Description

2',4'-Difluoro-2,2-Dimethylpropiophenone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical active ingredients and agrochemicals. It is essential for research and production in fine chemical, pharmaceutical, and agrochemical industries requiring precise fluorination for bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluorophenyl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination enhances efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers and liquid crystals with unique properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a substrate for exploring new fluorination methodologies.
• Life Science Research: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and probe molecule development.

Basic Information

Product Name	2',4'-Difluoro-2,2-Dimethylpropiophenone
CAS No.	898789-71-4
Molecular Formula	C11H12F2O
Molecular Weight	198.21 g/mol
Synonyms	2,2-Dimethyl-1-(2,4-difluorophenyl)propan-1-one; 1-(2,4-Difluorophenyl)-2,2-dimethylpropan-1-one; α,α-Dimethyl-2,4-difluorophenylacetone; 2,4-DFDMP; Difluorodimethylpropiophenone
EINECS	Contact for details

Quality Control

Our 2',4'-Difluoro-2,2-Dimethylpropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.