Description

3'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone is a high-value, synthetically versatile organic intermediate characterized by its distinct halogenated aromatic structure. Its core value proposition lies in enabling precise molecular construction for advanced chemical synthesis, offering researchers and manufacturers a critical building block for creating complex target molecules. This compound is primarily needed by the pharmaceutical and agrochemical industries for the research and development of new active ingredients, where its specific substitution pattern allows for fine-tuning of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation herbicides, fungicides, or insecticides, leveraging the bioactivity of its halogenated phenylpropiophenone core.
• Advanced Material Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials where its molecular structure can influence material properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new synthetic pathways involving carbonyl and aryl halide functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches for clinical trials.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone
CAS No.	898789-66-7
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(o-tolyl)propan-1-one; 3-(2-Methylphenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; 3'-Chloro-4'-fluoro-3-(o-tolyl)propiophenone; 1-Propanone, 1-(3-chloro-4-fluorophenyl)-3-(2-methylphenyl)-; o-Tolyl 3-chloro-4-fluorophenyl ketone derivative; Propiophenone, 3'-chloro-4'-fluoro-3-(2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-3-(2-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.