Description

4'-Chloro-3'-Fluoro-3-(2-Methylphenyl)Propiophenone is a high-purity, specialized organic intermediate of significant importance in modern synthetic chemistry. Its value lies in its unique halogenated aromatic structure, which serves as a versatile building block for constructing more complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where its halogenated phenyl rings contribute to biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other catalytic processes to introduce complex substituted phenyl groups into target molecules.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation in related chemical production.

Basic Information

Product Name	4'-Chloro-3'-Fluoro-3-(2-Methylphenyl)Propiophenone
CAS No.	898789-64-5
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(4-Chloro-3-fluorophenyl)-3-(o-tolyl)propan-1-one; 3-(2-Methylphenyl)-1-(4-chloro-3-fluorophenyl)propan-1-one; 4'-Chloro-3'-fluoro-3-(o-tolyl)propiophenone; 898789-64-5; Propiophenone, 4'-chloro-3'-fluoro-3-(2-methylphenyl)-; 1-Propanone, 1-(4-chloro-3-fluorophenyl)-3-(2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-Fluoro-3-(2-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.