Description

3'-Chloro-3-(3-Fluorophenyl)Propiophenone is a specialized organic intermediate featuring a propiophenone core substituted with chloro and fluorophenyl groups. This compound matters for its role as a critical building block in the synthesis of complex, high-value molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process development teams in the fine chemical, agrochemical, and advanced material industries seeking to introduce specific halogenated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorophenyl and chlorophenyl groups can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, or polymers where its aromatic and halogenated structure can influence electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving clients in life sciences.

Basic Information

Product Name	3'-Chloro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898789-08-7
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(3-Chlorophenyl)-3-(3-fluorophenyl)-1-propanone; 3'-Chloro-3-(3-fluorophenyl)propiophenone; 3-Chloro-3'-(3-fluorophenyl)propiophenone; 1-Propanone, 1-(3-chlorophenyl)-3-(3-fluorophenyl)-; 3-(3-Fluorophenyl)-1-(3-chlorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3'-Chloro-3-(3-Fluorophenyl)Propiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.