Description

3'-Bromo-3-(3-Fluorophenyl)Propiophenone is a high-purity, fluorinated and brominated aromatic ketone building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce complex aryl motifs.
• Academic & Contract Research: A valuable tool for universities and CROs (Contract Research Organizations) conducting research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	3'-Bromo-3-(3-Fluorophenyl)Propiophenone
CAS No.	898789-02-1
Molecular Formula	C15H12BrFO
Molecular Weight	307.16 g/mol
Synonyms	1-(3-Bromophenyl)-3-(3-fluorophenyl)-1-propanone; 3'-Bromo-3-(3-fluorophenyl)propiophenone; 3-Bromo-3'-fluoropropiophenone; 1-Propanone, 1-(3-bromophenyl)-3-(3-fluorophenyl)-; 3-(3-Fluorophenyl)-1-(3-bromophenyl)propan-1-one; 3'-Bromo-3-fluoropropiophenone (ambiguous); β-(3-Fluorophenyl)-3'-bromopropiophenone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.