Description

3-(3-Fluorophenyl)-4'-Thiomethylpropiophenone is a specialized fluorinated aromatic ketone derivative featuring a thiomethyl functional group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new generation herbicides and fungicides with enhanced efficacy.
• Ligand & Catalyst Development: Serves as a core structure for creating specialized ligands in transition metal catalysis and asymmetric synthesis.
• Material Science: Intermediate for synthesizing functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorophore-tagged molecules for cellular imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	3-(3-Fluorophenyl)-4'-Thiomethylpropiophenone
CAS No.	898789-00-9
Molecular Formula	C16H15FOS
Molecular Weight	274.35 g/mol
Synonyms	1-[4-(Methylthio)phenyl]-3-(3-fluorophenyl)propan-1-one; 3-(3-Fluorophenyl)-1-[4-(methylsulfanyl)phenyl]propan-1-one; 4'-Thiomethyl-3-(3-fluorophenyl)propiophenone; 3-Fluoro-3'-phenyl-4'-(methylthio)propiophenone; Propiophenone, 3-(3-fluorophenyl)-4'-(methylthio)-; 898789-00-9; FCAS 898789-00-9
EINECS	Contact for details

Quality Control

Our production of 3-(3-Fluorophenyl)-4'-Thiomethylpropiophenone adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to supply chain transparency and can provide material traceability documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.