Description

2'-Cyano-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block, a key intermediate in advanced organic synthesis. Its molecular structure, featuring both cyano and fluorophenyl groups, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, such as novel cyano-alkylation or fluorophenyl coupling reactions.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2'-Cyano-3-(3-Fluorophenyl)Propiophenone
CAS No.	898788-79-9
Molecular Formula	C₁₆H₁₂FNO
Molecular Weight	253.27 g/mol
Synonyms	3-(3-Fluorophenyl)-2-cyanopropiophenone; 1-(2-Cyanophenyl)-3-(3-fluorophenyl)propan-1-one; 2-Cyano-3-(3-fluorophenyl)propiophenone; 3-(3-Fluorophenyl)-2-cyanopropiophenone; 898788-79-9; Propiophenone, 2'-cyano-3-(3-fluorophenyl)-; 2-Cyano-3-(3-fluorophenyl)-1-phenylpropan-1-one
EINECS	Contact for details

Quality Control

Our 2'-Cyano-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for impurity profiling. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are consistently monitored to meet the high standards demanded in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.