Description

3-(4-Chlorophenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research institutions and manufacturers in the fine chemical and life sciences sectors for developing novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and fluorination studies to create complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	3-(4-Chlorophenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898788-51-7
Molecular Formula	C15H9ClF3O
Molecular Weight	288.68 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3',4',5'-Trifluoro-3-(4-chlorophenyl)propiophenone; 3-(4-Chlorophenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; Propiophenone, 3-(4-chlorophenyl)-3',4',5'-trifluoro-; 898788-51-7; 3-(p-Chlorophenyl)-3',4',5'-trifluoropropiophenone
EINECS	Contact for details

Quality Control

Our production of 3-(4-Chlorophenyl)-3',4',5'-Trifluoropropiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.