Description

2'-Chloro-3-(4-Chlorophenyl)-4'-Fluoropropiophenone is a high-purity, specialized organic intermediate featuring a unique halogenated aromatic ketone structure. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise chemical functionality for advanced research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or metabolic disorders.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides with specific modes of action.
• Material Science: Used in the research and development of advanced organic materials, such as liquid crystals or specialty polymers.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecular architectures, leveraging its reactive ketone and halogen functional groups.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory chemistry and method development.

Basic Information

Product Name	2'-Chloro-3-(4-Chlorophenyl)-4'-Fluoropropiophenone
CAS No.	898788-33-5
Molecular Formula	C15H11Cl2FO
Molecular Weight	297.15 g/mol
Synonyms	1-(2-Chlorophenyl)-3-(4-chlorophenyl)-3-fluoropropan-1-one; 3-(4-Chlorophenyl)-1-(2-chlorophenyl)-3-fluoropropan-1-one; 2'-Chloro-3-(4-chlorophenyl)-4'-fluoropropiophenone; 898788-33-5; Propiophenone, 2'-chloro-3-(4-chlorophenyl)-4'-fluoro-; 3-Fluoro-1,3-bis(4-chlorophenyl)propan-1-one (related isomer); Halogenated propiophenone derivative
EINECS	Contact for details

Quality Control

Our 2'-Chloro-3-(4-Chlorophenyl)-4'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards where required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.