Description

3-(4-Chlorophenyl)-2'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific halogenated structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorinated and chlorinated motifs into target molecules.

Application

• As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Used in agrochemical research for the development of new herbicides and pesticides with enhanced activity and selectivity.
• Serves as a versatile building block in organic chemistry for constructing complex fluorinated and chlorinated aromatic systems.
• Employed in material science for the synthesis of specialty polymers and liquid crystals with tailored electronic properties.
• Facilitates process chemistry and route scouting for the scalable production of fine chemicals.
• Utilized in academic and industrial R&D for exploring new chemical reactions and catalytic methodologies involving halogenated ketones.

Basic Information

Product Name	3-(4-Chlorophenyl)-2'-Fluoropropiophenone
CAS No.	898788-23-3
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-(4-chlorophenyl)propiophenone; 3-(p-Chlorophenyl)-2'-fluoropropiophenone; 3-(4-Chlorophenyl)-1-(2-fluorophenyl)propan-1-one; Propiophenone, 3-(4-chlorophenyl)-2'-fluoro-; 898788-23-3; 3-(4-Chlorophenyl)-2-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.