Description

4'-Bromo-3-(4-Chlorophenyl)-3'-Fluoropropiophenone is a high-value, multi-functional halogenated aromatic ketone intermediate. This compound is critical for its role in advanced organic synthesis, particularly in constructing complex molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its specific substitution pattern makes it a versatile building block for medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and advanced organic materials with specific electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.

Basic Information

Product Name	4'-Bromo-3-(4-Chlorophenyl)-3'-Fluoropropiophenone
CAS No.	898788-12-0
Molecular Formula	C15H11BrClFO
Molecular Weight	356.60 g/mol
Synonyms	1-(4-Bromophenyl)-3-(4-chlorophenyl)-3-fluoropropan-1-one; 3-(4-Chlorophenyl)-1-(4-bromophenyl)-3-fluoropropan-1-one; 4'-Bromo-3-(4-chlorophenyl)-3'-fluoropropiophenone; 898788-12-0; 3-Fluoro-3-(4-chlorophenyl)-1-(4-bromophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-(4-Chlorophenyl)-3'-Fluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support custom synthesis and can tailor purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.