Description

3'-Thiomorpholinomethyl-3,4,5-Trifluorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluorobenzophenone core modified with a thiomorpholinomethyl moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in the development of fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex, fluorinated drug molecules, particularly in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) under Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) conditions.
• Fluorinated Compound Library Synthesis: Essential for creating specialized chemical libraries for high-throughput screening in drug discovery programs.
• Custom Synthesis Projects: Employed by fine chemical suppliers for bespoke manufacturing projects requiring high-purity, complex heterocyclic fluorinated intermediates.

Basic Information

Product Name	3'-Thiomorpholinomethyl-3,4,5-Trifluorobenzophenone
CAS No.	898788-02-8
Molecular Formula	C18H15F3NO2S
Molecular Weight	366.38 g/mol
Synonyms	3,4,5-Trifluoro-3'-(thiomorpholinomethyl)benzophenone; 3'-(Thiomorpholin-4-ylmethyl)-3,4,5-trifluorobenzophenone; 3,4,5-Trifluorobenzophenone-3'-ylmethyl thiomorpholine; Benzophenone, 3,4,5-trifluoro-3'-(thiomorpholinomethyl)-; 898788-02-8; 3,4,5-Trifluoro-3'-(thiomorpholin-4-ylmethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 3'-Thiomorpholinomethyl-3,4,5-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry standards for research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.