Description

3-(4-Chlorophenyl)-3'-Fluoropropiophenone is a high-purity fluorinated and chlorinated aromatic ketone intermediate. This compound is valued for its unique molecular scaffold, which is integral to the synthesis of more complex chemical entities. It is primarily sought by research and development teams and process chemists in the pharmaceutical and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging the biological activity of its fluorinated and chlorinated phenyl groups.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the creation of fluorinated organic compounds for electronic display and lighting applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to create complex biaryl structures for various research purposes.
• Chemical Reference Standard: Used in analytical laboratories as a high-purity standard for method development and quality control testing.

Basic Information

Product Name	3-(4-Chlorophenyl)-3'-Fluoropropiophenone
CAS No.	898787-91-2
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(3-fluorophenyl)-1-propanone; 3'-Fluoro-3-(4-chlorophenyl)propiophenone; 3-(4-Chlorophenyl)-1-(3-fluorophenyl)-1-propanone; 898787-91-2; Propiophenone, 3-(4-chlorophenyl)-3'-fluoro-; 3-(p-Chlorophenyl)-3'-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our production of 3-(4-Chlorophenyl)-3'-Fluoropropiophenone adheres to strict in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.