Description

3-(2-Acetoxyphenyl)-1,1,1-Trifluoro-2-Propanone is a high-purity trifluoromethyl ketone derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical reactivity, particularly in introducing the trifluoromethyl group, which is essential for modulating the physical and biological properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and coatings with tailored properties like chemical resistance.
• Fluorine Chemistry: An essential reagent for academic and industrial research focused on organofluorine chemistry and methodology development.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and metal-organic frameworks (MOFs) for asymmetric catalysis.

Basic Information

Product Name	3-(2-Acetoxyphenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	898787-75-2
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	1-[2-(Acetyloxy)phenyl]-3,3,3-trifluoro-2-propanone; 2'-Acetoxy-3,3,3-trifluoropropiophenone; 3,3,3-Trifluoro-1-(2-hydroxyphenyl)-2-propanone acetate; 3,3,3-Trifluoro-2-propanone, 1-(2-acetoxyphenyl)-; 1-(2-Acetoxyphenyl)-3,3,3-trifluoro-2-propanone; TFAP derivative; Trifluoromethyl ketone acetate intermediate
EINECS	Contact for details

Quality Control

Our 3-(2-Acetoxyphenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.