Description

3-(3-Bromophenyl)-1,1,1-Trifluoro-2-Propanone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique structure, featuring both a bromo substituent and a trifluoromethyl ketone group, makes it a versatile intermediate for introducing fluorinated motifs into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in the synthesis of molecules with trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorinated components.
• Cross-Coupling Reactions: The bromophenyl moiety acts as a handle for palladium-catalyzed reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Fluorine Chemistry Building Block: Integral for synthesizing a wide range of fluorinated fine chemicals and complex organic compounds in academic and industrial laboratories.

Basic Information

Product Name	3-(3-Bromophenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	898787-59-2
Molecular Formula	C9H6BrF3O
Molecular Weight	267.04 g/mol
Synonyms	1-(3-Bromophenyl)-3,3,3-trifluoropropan-1-one; 3-Bromo-α,α,α-trifluoroacetophenone; 3'-Bromo-α,α,α-trifluoroacetophenone; 3-Bromophenyl trifluoromethyl ketone; 3-Bromo-ω,ω,ω-trifluoroacetophenone; m-Bromo-α,α,α-trifluoroacetophenone; 3-Bromo-1-(trifluoroacetyl)benzene
EINECS	Contact for details

Quality Control

Our 3-(3-Bromophenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.