Description

3-(2-Bromophenyl)-1,1,1-Trifluoro-2-Propanone is a high-value fluorinated aromatic ketone building block, essential for advanced synthetic chemistry. Its unique structure, featuring a bromine substituent and a trifluoromethyl ketone group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing the trifluoromethyl group to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromophenyl and trifluoromethyl motifs contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for electronic materials, liquid crystals, and polymers with specific optical or thermal properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(2-Bromophenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	898787-57-0
Molecular Formula	C9H6BrF3O
Molecular Weight	267.04 g/mol
Synonyms	2-Bromo-α,α,α-trifluoroacetophenone; 1-(2-Bromophenyl)-2,2,2-trifluoroethanone; 2'-Bromo-α,α,α-trifluoroacetophenone; 2-Bromophenyl trifluoromethyl ketone; α,α,α-Trifluoro-2'-bromoacetophenone; 2-Bromo-α,α,α-trifluoroacetophenone; 1-(2-Bromophenyl)-2,2,2-trifluoro-1-ethanone
EINECS	Contact for details

Quality Control

Our 3-(2-Bromophenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.