Description

3-(3-Chlorophenyl)-3',5'-Difluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic structure. This compound is of critical importance for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides due to its halogenated phenyl and difluoro motifs.
• Material Science Research: Serves as a precursor for the development of specialty polymers and advanced organic materials with specific electronic properties.
• Chemical Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis: A versatile reagent for cross-coupling reactions and the construction of complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	3-(3-Chlorophenyl)-3',5'-Difluoropropiophenone
CAS No.	898787-46-7
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(3-Chlorophenyl)-3-(3,5-difluorophenyl)propan-1-one; 3',5'-Difluoro-3-chloropropiophenone; 3-Chloro-3',5'-difluoropropiophenone; Propiophenone, 3-(3-chlorophenyl)-3',5'-difluoro-; 898787-46-7; 3-(3-Chlorophenyl)-3,5-difluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-3',5'-Difluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.