Description

3-(5-Bromo-2-Methoxyphenyl)-1,1,1-Trifluoro-2-Propanone is a high-value trifluoromethyl ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both bromo and methoxy substituents on the aromatic ring, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

This specialized intermediate is designed for high-value synthesis in research and industrial settings. Key application areas include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a building block for creating specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and enzyme inhibitors for biochemical research.
• Fluorine Chemistry: A valuable substrate for exploring new fluorination reactions and synthesizing other fluorinated aromatic compounds.

Basic Information

Product Name	3-(5-Bromo-2-Methoxyphenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	898787-45-6
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	1-(5-Bromo-2-methoxyphenyl)-3,3,3-trifluoropropan-1-one; 3,3,3-Trifluoro-1-(5-bromo-2-methoxyphenyl)propan-1-one; 5'-Bromo-2'-methoxy-3,3,3-trifluoropropiophenone; 898787-45-6; 3-(5-Bromo-2-methoxyphenyl)-1,1,1-trifluoropropan-2-one; 1-(5-Bromo-2-methoxyphenyl)-3,3,3-trifluoroacetone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Quality is assured through analytical techniques including HPLC, GC, NMR, and mass spectrometry. We adhere to a cGMP-compliant quality management system for consistent batch-to-batch reproducibility, essential for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.