Description

3-(3-Chlorophenyl)-3',4'-Difluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both chlorophenyl and difluorophenyl moieties, making it a versatile precursor for the development of complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Research: Serves as a critical precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of its fluorinated and chlorinated structure.
• Material Science Chemistry: Used in the research and production of specialty polymers, liquid crystals, and advanced organic electronic materials where specific fluorine substitution patterns are required.
• Chemical Synthesis Scaffold: Acts as a versatile starting material for further functionalization, including reduction to alcohols, Grignard reactions, or incorporation into larger, more complex heterocyclic systems.
• Reference Standard: Supplied as a high-purity compound for use as an analytical standard in quality control (QC) and research laboratories for method development and validation.

Basic Information

Product Name	3-(3-Chlorophenyl)-3',4'-Difluoropropiophenone
CAS No.	898787-44-5
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(3-Chlorophenyl)-3-(3,4-difluorophenyl)propan-1-one; 3',4'-Difluoro-3-chloropropiophenone; 3-Chloro-3',4'-difluoropropiophenone; Propiophenone, 3-(3-chlorophenyl)-3',4'-difluoro-; 898787-44-5; 3-(3-Chlorophenyl)-3,4-difluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-3',4'-Difluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.