Description

3-(4-Biphenyl)-1,1,1-Trifluoro-2-Propanone is a high-purity trifluoromethyl ketone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity of the trifluoroacetyl group, which is essential for constructing complex molecules with enhanced metabolic stability and lipophilicity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients, particularly in medicinal chemistry for protease inhibitor research and in material science for specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially protease inhibitors and other bioactive molecules leveraging the trifluoromethyl group for improved pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the introduction of fluorine atoms can increase biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials, contributing to the development of materials with specific optical or electronic characteristics.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying enzyme mechanisms and protein-ligand interactions within biological systems.
• Fluorine Chemistry Studies: An important reagent in academic and industrial research focused on exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	3-(4-Biphenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	898787-43-4
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	1-[1,1'-Biphenyl]-4-yl-3,3,3-trifluoro-2-propanone; 3,3,3-Trifluoro-1-(4-phenylphenyl)propan-2-one; 4-Biphenyltrifluoroacetone; 1-(4-Biphenylyl)-3,3,3-trifluoro-2-propanone; 3,3,3-Trifluoro-2-propanone, 1-(1,1'-biphenyl-4-yl)-; (4-Biphenylyl)trifluoroacetone; p-Phenylphenyl Trifluoroacetone
EINECS	Contact for details

Quality Control

Our 3-(4-Biphenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.