Description

Ethyl 5-Trifluoroacetyl-2-Thenoate is a high-purity fluorinated heterocyclic building block, essential for advanced synthetic chemistry. Its core value lies in the trifluoroacetyl group, which introduces unique electronic and steric properties critical for modulating the activity of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic scaffolds found in active pharmaceutical ingredients (APIs), particularly in CNS and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and organic electronic materials with tailored properties.
• Fluorine Chemistry Research: An important reagent for studying the introduction and effects of trifluoromethyl ketone functionalities in organic molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Item	Detail
Product Name	Ethyl 5-Trifluoroacetyl-2-Thenoate
CAS No.	898787-39-8
Molecular Formula	C9H7F3O3S
Molecular Weight	252.21 g/mol
Synonyms	Ethyl 5-(trifluoroacetyl)thiophene-2-carboxylate; 2-Thenoic acid, 5-(trifluoroacetyl)-, ethyl ester; 5-Trifluoroacetyl-2-thiophenecarboxylic Acid Ethyl Ester; Ethyl 5-(Trifluoroacetyl)-2-thiophenecarboxylate; Thiophene-2-carboxylic acid, 5-(trifluoroacetyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Trifluoroacetyl-2-Thenoate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.