Description

3-(3-Chlorophenyl)-2'-Trifluoromethylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic and trifluoromethyl-substituted ketone structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents. Our supply ensures consistent quality and reliable availability for global R&D and production needs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	3-(3-Chlorophenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898787-26-3
Molecular Formula	C16H12ClF3O
Molecular Weight	312.72 g/mol
Synonyms	1-[3-(3-Chlorophenyl)propyl]-2-(trifluoromethyl)benzene; 3-Chloro-α,α,α-trifluoro-2'-methylpropiophenone; 2'-Trifluoromethyl-3-(3-chlorophenyl)propiophenone; 3-(3-Chlorophenyl)-1-(2-(trifluoromethyl)phenyl)propan-1-one; 898787-26-3; Propiophenone, 3-(3-chlorophenyl)-2'-(trifluoromethyl)-; 3-(3-Chlorophenyl)-2'-(trifluoromethyl)propiophenone
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chlorophenyl)-2'-Trifluoromethylpropiophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as identity, purity, and impurity profiles. Our quality commitment aligns with industry best practices to support your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.