Description

3'-Carboethoxy-2,2,2-Trifluoroacetophenone is a specialized fluorinated aromatic ketone ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the trifluoromethyl and ester functional groups, enabling precise molecular construction. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl motifs which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers and liquid crystals with unique thermal and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, condensations, and as a substrate for generating complex heterocyclic compounds in academic and industrial R&D settings.
• Fluorine Chemistry Studies: A valuable compound for investigating the influence of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	3'-Carboethoxy-2,2,2-Trifluoroacetophenone
CAS No.	898787-11-6
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	Ethyl 2,2,2-trifluoro-3-oxo-3-phenylpropanoate; 3-Oxo-3-phenyl-2,2,2-trifluoropropionic acid ethyl ester; Ethyl 3-oxo-3-phenyl-2,2,2-trifluoropropionate; 2,2,2-Trifluoro-3-oxo-3-phenylpropionic Acid Ethyl Ester; 3'-Ethoxycarbonyl-2,2,2-trifluoroacetophenone; 3-Phenyl-3-oxo-2,2,2-trifluoropropionic acid ethyl ester; α,α,α-Trifluoroacetoacetic acid ethyl ester phenyl derivative
EINECS	Contact for details

Quality Control

Our 3'-Carboethoxy-2,2,2-Trifluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.