Description

3-(3-Chlorophenyl)-4'-Fluoropropiophenone is a specialized organic intermediate featuring a propiophenone core substituted with both chloro and fluoro phenyl groups. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or building block for advanced polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis: A versatile reagent for cross-coupling reactions and the construction of complex heterocyclic compounds in academic and industrial laboratories.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in analytical chemistry.

Basic Information

Product Name	3-(3-Chlorophenyl)-4'-Fluoropropiophenone
CAS No.	898787-00-3
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(4-Fluorophenyl)-3-(3-chlorophenyl)propan-1-one; 4'-Fluoro-3'-(3-chlorophenyl)propiophenone; 3-Chloro-3'-(4-fluorobenzoyl)propiophenone; Propiophenone, 3-(3-chlorophenyl)-4'-fluoro-; 898787-00-3; 3-(3-Chlorophenyl)-4-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-4'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.