Description

2',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorinated aromatic ketone structure with a protected diol moiety. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Reagent: Used in advanced organic reactions, including cross-coupling and nucleophilic addition, to introduce complex fluorinated ketone functionalities.
• Agrochemical Research: Serves as a precursor in the development of new-generation, fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science: Investigated for the synthesis of specialty polymers and advanced organic electronic materials due to its fluorine content and stable dioxane group.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the discovery of new chemical entities (NCEs).

Basic Information

Item	Details
Product Name	2',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone
CAS No.	898786-88-4
Molecular Formula	C₁₆H₂₀F₂O₃
Molecular Weight	298.33 g/mol
Synonyms	4-(5,5-Dimethyl-1,3-dioxan-2-yl)-2',5'-difluorobutyrophenone; 2',5'-Difluoro-4-(5,5-dimethyl-1,3-dioxan-2-yl)-1-butanone; 1-(2,5-Difluorophenyl)-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one; DF-DDBP; Difluorodioxanyl Butyrophenone
EINECS	Contact for details

Quality Control

Our 2',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.