Description

2',4'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorinated valerophenone structure with a protected carbonyl group. This compound is of significant value in modern synthetic chemistry for its role as a key building block in the development of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a key building block for developing novel pesticides and herbicides, leveraging the fluorine atoms for enhanced biological activity and environmental stability.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for methodological studies involving fluorination reactions and the manipulation of protected carbonyl functionalities.
• Material Science Precursor: Potential use in the synthesis of specialized monomers or ligands for advanced polymeric materials and catalysts.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	2',4'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone
CAS No.	898786-85-1
Molecular Formula	C17H22F2O3
Molecular Weight	312.36 g/mol
Synonyms	5,5-Dimethyl-2-[5-(2,4-difluorophenyl)-1-oxopentyl]-1,3-dioxane; 5-(2,4-Difluorophenyl)-1-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one; 2',4'-Difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone; 898786-85-1; Difluorinated Valerophenone Dioxane Derivative; Valerophenone, 2',4'-difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2',4'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we can support development projects requiring ICH stability guidelines or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.