Description

2',3'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorinated aromatic ketone structure. This compound is critical for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Synthesis: Used as a building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing.
• Organic Synthesis Research: Employed in academic and industrial R&D for developing new fluorination methodologies and exploring structure-activity relationships (SAR).
• Preclinical & Clinical Development: Supplied for the production of compounds used in pharmacological testing, toxicology studies, and early-stage clinical trial materials.
• Fine Chemical Production: Applicable in the synthesis of specialized fine chemicals where the introduction of a difluorophenyl ketone moiety is required.

Basic Information

Product Name	2',3'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone
CAS No.	898786-80-6
Molecular Formula	C₁₇H₂₂F₂O₃
Molecular Weight	312.36 g/mol
Synonyms	5-(5,5-Dimethyl-1,3-dioxan-2-yl)-2',3'-difluorovalerophenone; 1-[2,3-Difluorophenyl]-5-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one; 2',3'-Difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-1-phenylpentan-1-one; Valerophenone, 2',3'-difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-; DF-DDV Intermediate
EINECS	Contact for details

Quality Control

Our 2',3'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.