Description

5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-Trifluoromethylvalerophenone is a high-value, specialized organic intermediate featuring a protected carbonyl group and a trifluoromethyl aromatic moiety. This compound is critical for its role in advanced synthetic pathways, particularly in the development of complex, bioactive molecules where structural precision and functional group compatibility are paramount. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing specialty polymers or liquid crystals that require specific fluorinated aromatic structures.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in organic chemistry, particularly in reactions involving ketone protection/deprotection and fluorinated arenes.
• Custom Synthesis & Scale-Up: A critical material for custom synthesis organizations (CSOs) supporting clients from milligram-scale discovery to kilogram-scale process development.

Basic Information

Product Name	5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-Trifluoromethylvalerophenone
CAS No.	898786-67-9
Molecular Formula	C18H23F3O3
Molecular Weight	344.37 g/mol
Synonyms	2'-Trifluoromethyl-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone; 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-(2-(trifluoromethyl)phenyl)pentan-1-one; 1-(2-(Trifluoromethyl)phenyl)-5-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one; 898786-67-9; Valerophenone, 5-(5,5-dimethyl-1,3-dioxan-2-yl)-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-Trifluoromethylvalerophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All materials are characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. Certificates of Analysis (COA) detailing all critical quality attributes are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.