Description

3-(1,3-Dioxan-2-Yl)-3'-Trifluoromethylpropiophenone is a specialized organic building block featuring a dioxane-protected ketone and a trifluoromethylphenyl group. This compound matters as a high-value intermediate for synthesizing complex molecules, offering chemists a versatile handle for constructing pharmacophores and advanced materials. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for novel organic electronic materials or liquid crystals, leveraging its aromatic and ketone functionalities.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including cross-coupling and functional group transformation reactions.
• Custom Synthesis & Scale-Up: A critical starting material for custom manufacturing organizations (CMOs) engaged in producing kilogram to multi-kilogram quantities for clinical trial materials.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)-3'-Trifluoromethylpropiophenone
CAS No.	898786-57-7
Molecular Formula	C15H17F3O3
Molecular Weight	302.29 g/mol
Synonyms	3'-(Trifluoromethyl)-3-(1,3-dioxan-2-yl)propiophenone; 1-[3-(1,3-Dioxan-2-yl)propyl]-3-(trifluoromethyl)benzene; 3-(1,3-Dioxan-2-yl)-1-(3-(trifluoromethyl)phenyl)propan-1-one; 3-(2-(1,3-Dioxan-2-yl)ethyl)-α,α,α-trifluoroacetophenone; Propiophenone, 3-(1,3-dioxan-2-yl)-3'-(trifluoromethyl)-; 898786-57-7; 3-(1,3-Dioxan-2-yl)-3'-trifluoromethylpropiophenone
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-3'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.