Description

3-(1,3-Dioxan-2-Yl)-2'-Trifluoromethylpropiophenone is a specialized organic intermediate featuring a propiophenone core protected by a dioxane group and substituted with a trifluoromethyl moiety. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated aromatic ketone functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its specific electronic properties.
• Advanced Organic Synthesis: Employed in multi-step synthetic routes where the dioxane protecting group provides stability during subsequent reactions.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the incorporation of fluorine atoms into complex molecular architectures.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)-2'-Trifluoromethylpropiophenone
CAS No.	898786-55-5
Molecular Formula	C15H17F3O3
Molecular Weight	302.29 g/mol
Synonyms	2'-Trifluoromethyl-3-(1,3-dioxan-2-yl)propiophenone; 3-(1,3-Dioxan-2-yl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; 1-[2-(Trifluoromethyl)phenyl]-3-(1,3-dioxan-2-yl)-1-propanone; 2-(Trifluoromethyl)-β-(1,3-dioxan-2-yl)propiophenone; 898786-55-5; Propiophenone, 3-(1,3-dioxan-2-yl)-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-2'-Trifluoromethylpropiophenone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.