Description

4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Methoxybutyrophenone is a specialized organic compound featuring a butyrophenone core protected by a dioxane acetal group. This molecular architecture makes it a valuable protected ketone intermediate for advanced organic synthesis, particularly in the development of complex pharmaceutical molecules and fine chemicals. It is primarily utilized by research institutions and pharmaceutical R&D departments for constructing novel chemical entities where selective deprotection strategies are required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring ketone functionality introduced under mild conditions.
• Organic Synthesis Research: Serves as a versatile precursor in academic and industrial research for developing new synthetic methodologies and complex molecular scaffolds.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including advanced materials, agrochemicals, and performance chemicals.
• Chemical Biology Probes: Potential use in the development of molecular probes and tool compounds for biological target identification and validation studies.
• Process Chemistry Development: Employed in route scouting and optimization for scalable, cost-effective production of target molecules in pilot plants.

Basic Information

Product Name	4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Methoxybutyrophenone
CAS No.	898786-45-3
Molecular Formula	C₁₇H₂₄O₄
Molecular Weight	292.37 g/mol
Synonyms	4'-Methoxy-4-(5,5-dimethyl-1,3-dioxan-2-yl)butyrophenone; 1-[4-Methoxyphenyl]-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one; 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-4'-methoxybutyrophenone; Protected 4'-Methoxybutyrophenone Acetal; Dioxane-protected Ketone Intermediate; Butyrophenone, 4'-(methoxy)-, 4-(5,5-dimethyl-1,3-dioxan-2-yl)-; 898786-45-3
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Methoxybutyrophenone is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support custom synthesis and can tailor specifications to meet specific research or process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.