Description

5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-3'-Fluorovalerophenone is a high-value, specialized organic intermediate featuring a protected carbonyl group and a fluorinated aromatic ring. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly within advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific fluorinated motifs and ketone functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorination for metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or pesticides where the fluorovalerophenone moiety can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in the development of advanced electronic display materials and organic light-emitting diodes.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems, leveraging the fluorine atom as an NMR-active label.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic synthesis, particularly in reactions involving protected carbonyls and aryl fluorides.

Basic Information

Product Name	5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-3'-Fluorovalerophenone
CAS No.	898786-15-7
Molecular Formula	C₁₇H₂₃FO₃
Molecular Weight	294.36 g/mol
Synonyms	3'-Fluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone; 1-[3-Fluorophenyl]-5-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one; 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-3'-fluorovalerophenone; 3'-Fluorovalerophenone 5,5-dimethyl-1,3-dioxane ketal; Valerophenone, 5-(5,5-dimethyl-1,3-dioxan-2-yl)-3'-fluoro-
EINECS	Contact for details

Quality Control

Our 5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-3'-Fluorovalerophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.