Description

2'-Chloro-3-(1,3-Dioxan-2-Yl)Propiophenone is a specialized organic intermediate featuring a propiophenone core functionalized with both a chloro substituent and a 1,3-dioxane protecting group. This compound matters as a critical building block in advanced organic synthesis, enabling the controlled construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring a protected carbonyl or specific chiral centers.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive halogen and ketone functionalities.
• Organic Chemistry Research: Serves as a versatile substrate for methodological studies, including cross-coupling reactions, nucleophilic substitutions, and deprotection strategies.
• Material Science Precursor: Potential use in the synthesis of specialized monomers or ligands for advanced polymeric or coordination complex materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	2'-Chloro-3-(1,3-Dioxan-2-Yl)Propiophenone
CAS No.	898785-82-5
Molecular Formula	C13H15ClO3
Molecular Weight	254.71 g/mol
Synonyms	2'-Chloro-3-(1,3-dioxan-2-yl)-1-phenylpropan-1-one; 1-Propanone, 2'-chloro-3-(1,3-dioxan-2-yl)-1-phenyl-; 2-Chloro-3-(1,3-dioxan-2-yl)propiophenone; 898785-82-5; Propiophenone, 2'-chloro-3-(1,3-dioxan-2-yl)-; 3-(1,3-Dioxan-2-yl)-2'-chloropropiophenone
EINECS	Contact for details

Quality Control

Every batch of 2'-Chloro-3-(1,3-Dioxan-2-Yl)Propiophenone undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system supports the delivery of material suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.