Description

3'-Bromo-3-(1,3-Dioxan-2-Yl)Propiophenone is a specialized organic building block featuring a brominated aromatic ketone core protected by a 1,3-dioxane acetal group. This unique structure makes it a valuable intermediate for the synthesis of more complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's reactivity allows for selective transformations, enabling the construction of novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized propiophenone scaffold.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new therapeutic candidates.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, or insecticides where the bromine and protected ketone offer versatile sites for further chemical modification.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, dyes, and functional materials.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and catalysis.
• Custom Synthesis Projects: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3'-Bromo-3-(1,3-Dioxan-2-Yl)Propiophenone
CAS No.	898785-68-7
Molecular Formula	C13H15BrO3
Molecular Weight	299.16 g/mol
Synonyms	2-(3-Bromophenyl)-2-oxoethyl 1,3-dioxane; 1-(3-Bromophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3'-Bromo-3-(1,3-dioxolan-2-yl)propiophenone (common variant); 3-Bromo-ω-(1,3-dioxan-2-yl)acetophenone; Propiophenone, 3'-bromo-3-(1,3-dioxan-2-yl)-; 898785-68-7; (3-Bromophenyl)[3-(1,3-dioxan-2-yl)-1-oxopropyl] Ketone
EINECS	Contact for details

Quality Control

Every batch of 3'-Bromo-3-(1,3-Dioxan-2-Yl)Propiophenone is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP and ISO-guided applications where documentation and traceability are critical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.