Description

T-Butyl 3-Chloro-4-Pyridyl Ketone is a high-purity organic intermediate featuring a pyridine ring substituted with a chloro group and a tert-butyl ketone moiety. This specific molecular architecture makes it a versatile and critical building block for advanced chemical synthesis. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential herbicides and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Serves as a core building block for developing new-generation herbicides and plant growth regulators.
• Chemical Research & Development: Used in academic and industrial labs for exploring novel heterocyclic compounds and reaction pathways.
• Ligand and Catalyst Preparation: The pyridine nitrogen and ketone group allow for its use in creating specialized ligands for metal catalysis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers.

Basic Information

Item	Detail
Product Name	T-Butyl 3-Chloro-4-Pyridyl Ketone
CAS No.	898785-55-2
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	1-(3-Chloro-4-pyridinyl)-2,2-dimethyl-1-propanone; 3-Chloro-4-(2,2-dimethylpropanoyl)pyridine; 2,2-Dimethyl-1-(3-chloro-4-pyridinyl)-1-propanone; tert-Butyl 3-chloro-4-pyridyl ketone; 3-Chloro-4-pivaloylpyridine; 4-Pivaloyl-3-chloropyridine; 1-(3-Chloro-pyridin-4-yl)-2,2-dimethyl-propan-1-one
EINECS	Contact for details

Quality Control

Our T-Butyl 3-Chloro-4-Pyridyl Ketone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.