Description

3-(1,3-Dioxan-2-Yl)-4'-Iodopropiophenone is a specialized organic building block featuring a propiophenone core substituted with both a 1,3-dioxane protecting group and an iodine atom. This unique structure makes it a valuable intermediate for advanced synthetic chemistry, particularly in the development of complex pharmaceutical compounds and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic systems.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive aryl iodide moiety.
• Organic Synthesis Research: Used in academic and industrial R&D for exploring new synthetic pathways and creating complex organic molecules.
• Agrochemical Development: Intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Material Science Precursor: Potential starting material for the synthesis of organic electronic materials or liquid crystals.
• Chemical Biology Probes: Can be utilized to create tagged molecules for studying biological processes.

Basic Information

Item	Detail
Product Name	3-(1,3-Dioxan-2-Yl)-4'-Iodopropiophenone
CAS No.	898785-52-9
Molecular Formula	C13H15IO3
Molecular Weight	346.16 g/mol
Synonyms	4'-Iodo-3-(1,3-dioxan-2-yl)propiophenone; 1-[4-Iodophenyl]-3-(1,3-dioxan-2-yl)-1-propanone; 3-(1,3-Dioxan-2-yl)-1-(4-iodophenyl)propan-1-one; 898785-52-9; Propiophenone, 3-(1,3-dioxan-2-yl)-4'-iodo-; 4'-Iodo-β-(1,3-dioxan-2-yl)propiophenone
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-4'-Iodopropiophenone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.