Description

3-(1,3-Dioxan-2-Yl)-3'-Iodopropiophenone is a specialized iodinated aromatic ketone derivative featuring a dioxane-protecting group. This compound matters as a high-value synthetic intermediate, offering a reactive iodophenyl moiety and a protected carbonyl function for selective transformations in complex organic synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring aryl-iodide coupling reactions.
• Cross-Coupling Reactions: Serves as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form new carbon-carbon bonds.
• Organic Synthesis Research: Used in academic and industrial R&D for methodological studies and the development of new synthetic pathways.
• Ligand and Catalyst Precursor: Potential precursor for the synthesis of specialized ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the creation of organic electronic materials or liquid crystals, where the iodine atom can be further functionalized.
• Chemical Biology Probes: Can be utilized in the synthesis of molecular probes or tags for biochemical and cellular studies.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)-3'-Iodopropiophenone
CAS No.	898785-49-4
Molecular Formula	C13H15IO3
Molecular Weight	346.16 g/mol
Synonyms	3'-Iodo-3-(1,3-dioxan-2-yl)propiophenone; 3-(1,3-Dioxan-2-yl)-1-(3-iodophenyl)propan-1-one; 1-(3-Iodophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3-(1,3-Dioxan-2-yl)-3'-iodopropiophenone; Propiophenone, 3-(1,3-dioxan-2-yl)-3'-iodo-; 898785-49-4; 3-Iodophenyl 3-(1,3-dioxan-2-yl)propyl ketone
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-3'-Iodopropiophenone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.