Description

2'-Iodo-2-(2-Methoxyphenyl)Acetophenone is a specialized iodinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both an iodo substituent and a methoxyphenyl group, makes it a versatile precursor for constructing complex molecular frameworks through cross-coupling and functional group transformations. This compound is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry research for creating complex small molecules.
• Organic Synthesis Reagent: Serves as a versatile substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodoarene moiety.
• Ligand and Catalyst Development: Used in the research and preparation of novel ligands or organocatalysts where the methoxy and carbonyl groups can act as coordinating sites.
• Material Science Research: Employed as a monomer or precursor in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Agrochemical Intermediate: Potential use in the synthesis of novel herbicides, fungicides, or plant growth regulators requiring complex diaryl ketone structures.
• Academic & R&D: A valuable compound for university and institutional research in synthetic methodology development and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	2'-Iodo-2-(2-Methoxyphenyl)Acetophenone
CAS No.	898784-89-9
Molecular Formula	C15H13IO2
Molecular Weight	352.17 g/mol
Synonyms	2'-Iodo-2-(o-methoxyphenyl)acetophenone; 1-(2-Iodophenyl)-2-(2-methoxyphenyl)ethan-1-one; α-(2-Methoxyphenyl)-2'-iodoacetophenone; 2-(2-Methoxyphenyl)-1-(2-iodophenyl)ethanone; (2-Methoxyphenyl)(2-iodophenyl)methanone, methylene derivative; o-Methoxy-2'-iododesoxybenzoin
EINECS	Contact for details

Quality Control

Our 2'-Iodo-2-(2-Methoxyphenyl)Acetophenone is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.