Description

2-(4-Fluorophenyl)-3'-Iodoacetophenone is a high-value fluorinated and iodinated aromatic ketone building block. This compound is critical for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and materials science applications.
• Advanced Material Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological processes due to its halogen tags.
• Cross-Coupling Reactions: Acts as a versatile electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl systems.
• Agrochemical Research: Investigated as an intermediate for novel crop protection agents and herbicides.

Basic Information

Product Name	2-(4-Fluorophenyl)-3'-Iodoacetophenone
CAS No.	898784-85-5
Molecular Formula	C14H10FIO
Molecular Weight	340.13 g/mol
Synonyms	1-[3-Iodophenyl]-2-(4-fluorophenyl)ethanone; 3'-Iodo-4-fluorochalcone (precursor form); 2-(4-Fluorophenyl)-1-(3-iodophenyl)ethan-1-one; 3-Iodobenzoyl-4-fluorobenzyl; 898784-85-5; 4-Fluoro-3'-iodochalcone intermediate; Ethanone, 1-[3-iodophenyl]-2-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-3'-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.