Description

2-(2-Fluorophenyl)-3'-Iodoacetophenone is a specialized fluorinated and iodinated acetophenone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique bifunctional structure, featuring both fluorine and iodine substituents, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used to develop novel pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Building block for synthesizing specialty polymers and liquid crystals with tailored electronic properties.
• Cross-Coupling Reactions: The iodine moiety serves as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Utilized in creating fluorescent or radiolabeled probes for imaging and diagnostic applications.
• Academic & Industrial R&D: Fundamental research tool in methodology development for introducing fluorine and aryl-iodide functional groups.

Basic Information

Product Name	2-(2-Fluorophenyl)-3'-Iodoacetophenone
CAS No.	898784-75-3
Molecular Formula	C14H10FIO
Molecular Weight	340.13 g/mol
Synonyms	1-[3-Iodophenyl]-2-(2-fluorophenyl)ethanone; 3'-Iodo-2'-fluoro desoxybenzoin; 2-Fluoro-3'-iodochalcone precursor; (2-Fluorophenyl)(3-iodophenyl)methanone; 898784-75-3; Ethanone, 1-[3-iodophenyl]-2-(2-fluorophenyl)-; 1-(3-Iodophenyl)-2-(2-fluorophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluorophenyl)-3'-Iodoacetophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by IR, NMR), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.