Description

3'-Bromo-2-(4-Fluorophenyl)Acetophenone CAS NO 898784-71-9 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromo and fluoro-substituted aromatic structure. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical companies engaged in the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development and production of novel pesticides and herbicides, where the bromo and fluoro substituents can enhance biological activity and stability.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials with specific electronic or optical properties.
• Organic Synthesis: A versatile building block for constructing complex molecular architectures in academic and industrial research, enabling carbon-carbon and carbon-heteroatom bond formations.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions, which are essential in asymmetric synthesis and process chemistry.

Basic Information

Product Name	3'-Bromo-2-(4-Fluorophenyl)Acetophenone
CAS No.	898784-71-9
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	1-(3-Bromophenyl)-2-(4-fluorophenyl)ethanone; 3'-Bromo-4-fluoro desoxybenzoin; 2-(4-Fluorophenyl)-1-(3-bromophenyl)ethan-1-one; α-(4-Fluorophenyl)-3-bromoacetophenone; (3-Bromophenyl)(4-fluorophenyl)methanone, methylene; 898784-71-9; Ethanone, 1-(3-bromophenyl)-2-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2-(4-Fluorophenyl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.