Description

3'-Bromo-2-(3-Fluorophenyl)Acetophenone is a high-purity, synthetically valuable aromatic ketone building block, distinguished by its strategically positioned bromine and fluorine substituents. This compound matters as a critical intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	3'-Bromo-2-(3-Fluorophenyl)Acetophenone
CAS No.	898784-69-5
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	1-(3-Bromophenyl)-2-(3-fluorophenyl)ethanone; 3'-Bromo-3-fluorobenzyl phenyl ketone; 2-(3-Fluorophenyl)-1-(3-bromophenyl)ethan-1-one; 3-Bromo-3'-fluorobenzophenone (common misnomer); α-(3-Fluorophenyl)-3'-bromoacetophenone; (3-Bromophenyl)(3-fluorophenyl)methanone (tautomeric form); 898784-69-5; BFPBAK
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2-(3-Fluorophenyl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize contact with moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.