Description

2'-Bromo-2-(3-Fluorophenyl)Acetophenone is a high-purity, specialized organic building block featuring both bromo and fluoro substituents on an acetophenone core structure. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, enabling the construction of complex molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides and fungicides, leveraging the bioactivity imparted by the halogenated aromatic system.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	2'-Bromo-2-(3-Fluorophenyl)Acetophenone
CAS No.	898784-67-3
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	1-(2-Bromophenyl)-2-(3-fluorophenyl)ethan-1-one; 2'-Bromo-2-(3-fluorophenyl)acetophenone; α-Bromo-3-fluoroacetophenone (related); 2-Bromo-2'-(3-fluorophenyl)acetophenone; (2-Bromophenyl)(3-fluorophenyl)methanone (tautomer consideration); 3-Fluoro-2-bromoacetophenone derivative
EINECS	Contact for details

Quality Control

Every batch of 2'-Bromo-2-(3-Fluorophenyl)Acetophenone is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.