Description

2'-Bromo-2-(2-Fluorophenyl)Acetophenone is a specialized brominated and fluorinated aromatic ketone, serving as a crucial synthetic intermediate in advanced organic chemistry. Its unique bifunctional structure makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors seeking to introduce specific halogenated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the fluorine and bromine substituents which can modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the halogenated phenyl groups contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) precursors or liquid crystals, where fluorinated aromatics are critical for performance.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Item	Detail
Product Name	2'-Bromo-2-(2-Fluorophenyl)Acetophenone
CAS No.	898784-61-7
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	2'-Bromo-2-(2-fluorophenyl)acetophenone; 1-(2-Bromophenyl)-2-(2-fluorophenyl)ethanone; α-Bromo-2'-fluoro desoxybenzoin; 2-Bromo-2'-(2-fluorophenyl)acetophenone; (2-Bromophenyl)(2-fluorophenyl)methanone (tautomeric form); 2-Fluoro-α-bromodesoxybenzoin; Ethanone, 1-(2-bromophenyl)-2-(2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2'-Bromo-2-(2-Fluorophenyl)Acetophenone is produced and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis workflows. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation, to verify identity and quality. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.