Description

2-(3,4,5-Trifluorobenzoyl)Oxazole is a high-value fluorinated heterocyclic building block, specifically designed for advanced organic synthesis. This compound is critical for introducing the unique physicochemical properties of fluorine into complex molecular architectures, enhancing metabolic stability and lipophilicity. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides where the trifluoromethylbenzoyl moiety contributes to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and heterocyclic structure.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Cross-Coupling Reactions: Functions as an electrophilic coupling partner in palladium-catalyzed reactions for constructing biaryl systems.

Basic Information

Product Name	2-(3,4,5-Trifluorobenzoyl)Oxazole
CAS No.	898784-54-8
Molecular Formula	C10H4F3NO2
Molecular Weight	227.14 g/mol
Synonyms	2-(3,4,5-Trifluorobenzoyl)-1,3-oxazole; Oxazole, 2-(3,4,5-trifluorobenzoyl)-; 3,4,5-Trifluorophenyl(oxazol-2-yl)methanone; 898784-54-8; (3,4,5-Trifluorophenyl)(oxazol-2-yl)methanone; 2-(3,4,5-Trifluorobenzoyl)oxazole; Methanone, (3,4,5-trifluorophenyl)-2-oxazolyl-
EINECS	Contact for details

Quality Control

Every batch of 2-(3,4,5-Trifluorobenzoyl)Oxazole is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure high purity and consistency for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.