Description

2-(3-Cyanophenyl)-3'-Trifluoromethylacetophenone is a high-value, multi-functional aromatic ketone building block. This compound is engineered for advanced synthesis, offering a unique combination of a cyano group and a trifluoromethyl group on a biphenyl-acetophenone scaffold, which is critical for modulating the electronic and steric properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing groups.
• Ligand and Catalyst Development: Employed in the design of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	2-(3-Cyanophenyl)-3'-Trifluoromethylacetophenone
CAS No.	898784-53-7
Molecular Formula	C16H10F3NO
Molecular Weight	289.25 g/mol
Synonyms	1-[3-(3-Cyanophenyl)phenyl]-2,2,2-trifluoroethanone; 3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-acetonitrile; 2-(3-Cyanophenyl)-3'-(trifluoromethyl)acetophenone; 3-(3-Trifluoromethylbenzoyl)benzonitrile; 3-Cyanophenyl 3'-trifluoromethyl phenyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Cyanophenyl)-3'-Trifluoromethylacetophenone is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.